BETA THALASSEMIA DISEASE

ABOUT SICKLE CELL BETA THALASSEMIA DISEASE

IN PATIENTS WITH SICKLE CELL BETA THALASSEMIA DISEASE, THERE IS A DECREASE IN HEMOGLOBIN PRODUCTION WHICH CAUSES SMALLER RED BLOOD CELLS.

WHEN BETA THALASSEMIA GENES ARE IN COMBINATION WITH THE SICKLE GENE,  IT IS  KNOWN AS SICKLE CELL BETA THALASSEMIA DISEASE.

THERE ARE TWO KINDS OF SICKLE CELL BETA THALASSEMIA DISEASE  (SBTHAL):

  • +THAL                                                                                                       couple
  • Sβ°THAL.

INDIVIDUALS WITH Sβ+THAL HAVE:

• SPLEENS THAT FUNCTION

• FEWER INFECTIONS

• FEWER PAIN EPISODES, AND

• LESS ORGAN DAMAGE DUE TO HEMOGLOBIN “A” (NORMAL) NOT BEING COMPLETELY SUPPRESSED.

PERSONS WITH Sβ°THAL HAVE:

•VERY SEVERE DISEASE — THE SAME AS SICKLE CELL ANEMIA.

  • SPLEENS THAT STOP WORKING LATER IN CHILDHOOD
  • ENLARGEMENT OF THE SPLEEN IS COMMON INTO ADULTHOOD.

•PAIN EPISODES

  • ORGAN DAMAGE
  • PROGNOSIS MAY BE SIMILAR TO, OR EVEN WORSE, FOR BONE AND EYE PROBLEMS WHEN COMPARED TO SICKLE CELL ANEMIA.